Peptiduria presumably caused by aminopeptidase-P deficiency. A new inborn error of metabolism

@article{Blau1988PeptiduriaPC,
  title={Peptiduria presumably caused by aminopeptidase-P deficiency. A new inborn error of metabolism},
  author={Nenad Blau and Alois Niederwieser and David H Shmerling},
  journal={Journal of Inherited Metabolic Disease},
  year={1988},
  volume={11},
  pages={240-242}
}
Aminopeptidase-P (APP; EC 3.4.11.9) is an exopeptidase highly specific in cleaving the N-terminal imino bond in oligopeptides of an Xaa-Pro-sequence (Yaron and Berger, 1970). Active participation of APP in collagen metabolism, as well as a role in inactivation of biologically active peptides, has been proposed (Fleminger and Yaron, 1983); however its real biological function is still unknown. We report on a 5-month-old boy with epilepsy, and his healthy 5-year-old brother, both of whom were… CONTINUE READING

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Aminopeptidases in Biology and Disease

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European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies • 1992

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