Peptidomimetics and metalloprotease inhibitors as anticancer drugs

  title={Peptidomimetics and metalloprotease inhibitors as anticancer drugs},
  author={Su Li and XU WenFang},
  • Su Li, XU WenFang
  • Published 2009
Peptidomimetics with three types, as the structural or functional mimetics of natural active peptides, can preserve the bioactivity and improve the bioavailability and the specificity towards the targets of the lead peptides. Peptidomimetics of high bioactivity can be designed through various ways including conformation restriction, modification and non-peptide design. Recently the concentration on the development of cancer chemotherapeutic drugs was transferred from cytotoxic drugs to target… CONTINUE READING


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