Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata.

@article{Ma2010PeptidomicsAG,
  title={Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata.},
  author={Yufang Ma and Cunbao Liu and Xiu-hong Liu and Jing Wu and Hailong Yang and Yipeng Wang and Jianxu Li and Haining Yu and Ren Lai},
  journal={Genomics},
  year={2010},
  volume={95 1},
  pages={66-71}
}
Much attention has been paid on amphibian peptides for their wide-ranging pharmacological properties, clinical potential, and gene-encoded origin. More than 300 antimicrobial peptides (AMPs) from amphibians have been studied. Peptidomics and genomics analysis combined with functional test including microorganism killing, histamine-releasing, and mast cell degranulation was used to investigate antimicrobial peptide diversity. Thirty-four novel AMPs from skin secretions of Rana nigrovittata were… CONTINUE READING