Peptidology: short amino acid modules in cell biology and immunology

  title={Peptidology: short amino acid modules in cell biology and immunology},
  author={Guglielmo Lucchese and Angela Stufano and Brett Trost and Anthony J. Kusalik and Darja Kanduc},
  journal={Amino Acids},
Short amino acid motifs, either linear sequences or discontinuous amino acid groupings, can interact with specific protein domains, so exerting a central role in cell adhesion, signal transduction, hormone activity, regulation of transcript expression, enzyme activity, and antigen-antibody interaction. Here, we analyze the literature for such critical short amino acid motifs to determine the minimal peptide length involved in biologically important interactions. We report the pentapeptide unit… CONTINUE READING

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