Peptidoglycan recognition proteins (PGRPs).

  title={Peptidoglycan recognition proteins (PGRPs).},
  author={Roman Dziarski},
  journal={Molecular immunology},
  volume={40 12},
Innate immune system recognizes microorganisms through a series of pattern recognition receptors that are highly conserved in evolution. Peptidoglycan recognition proteins (PGRPs) are pattern recognition molecules that are conserved from insects to mammals and recognize bacteria and their unique cell wall component, peptidoglycan (PGN). Drosophila, mosquito, and mammals have families of 13, 7, and 4 PGRP genes, respectively, and some of these genes are alternatively spliced. PGRPs are… CONTINUE READING
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