Peptide tyrosine phenylalanine: a novel neuropeptide F-related nonapeptide from the brain of the squid, Loligo vulgaris.

@article{Smart1992PeptideTP,
  title={Peptide tyrosine phenylalanine: a novel neuropeptide F-related nonapeptide from the brain of the squid, Loligo vulgaris.},
  author={Darren Smart and Chris Shaw and Colin Fredrick Johnston and Lars Thim and David W. Halton and Keith Deans Buchanan},
  journal={Biochemical and biophysical research communications},
  year={1992},
  volume={186 3},
  pages={1616-23}
}
A novel nonapeptide, sequence YAIVARPRFamide, was isolated from brain extracts of the squid, L. vulgaris. Designated peptide tyrosine phenylalanine (PYF), the peptide shows marked homology with the C-terminal nonapeptides of pancreatic polypeptide and neuropeptide F (NPF) from a number of sources. If PYF is the C-terminal nonapeptide of squid NPF, then it may be derived by a novel processing mechanism involving specific cleavage between two TYR residues. PYF may be a highly truncated, receptor… CONTINUE READING

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