Peptide-targeted radionuclide therapy for melanoma.

  title={Peptide-targeted radionuclide therapy for melanoma.},
  author={Yubin Miao and Thomas P Quinn},
  journal={Critical reviews in oncology/hematology},
  volume={67 3},
Melanocortin-1 receptor (MC1-R) and melanin are two attractive melanoma-specific targets for peptide-targeted radionuclide therapy for melanoma. Radiolabeled peptides targeting MC1-R/melanin can selectively and specifically target cytotoxic radiation generated from therapeutic radionuclides to melanoma cells for cell killing, while sparing the normal tissues and organs. This review highlights the recent advances of peptide-targeted radionuclide therapy of melanoma targeting MC1-R and melanin… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 90 references

203 Pblabeled alphamelanocyte stimulating hormone peptide as an imaging probe for melanoma detection

Y Miao, SD Figueroa, DR Fisher
J Nucl Med • 2008

Cancer statistics, 2008.

CA: a cancer journal for clinicians • 2008

Alpha-melanocyte stimulating hormone peptide-targeted melanoma imaging.

Frontiers in bioscience : a journal and virtual library • 2007

Indication for different mechanisms of kidney uptake of radiolabeled peptides.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine • 2007

Small - animal PET of melanocortin 1 receptor expression using a 18 Flabeled melanocytestimulating hormone analog

Z Cheng, L Zhang, E Graves
J Nucl Med • 2007

Synthesis and biological evaluation of 64 Culabled rheniumcyclized MSH peptide analogs using a crossbridged cyclam chelator

L Wei, C Butcher, Y Miao
J Nucl Med • 2007

Effects of therapy with [ 177 LuDOTA 0 , Tyr 3 ] Octreotate in patients with paraganglioma , meningioma , small cell lung carcinoma , and melanoma

M vanEssen, EP Krenning, PP Kooij
J Nucl Med • 2006

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