Peptide-targeted radionuclide therapy for melanoma.

@article{Miao2008PeptidetargetedRT,
  title={Peptide-targeted radionuclide therapy for melanoma.},
  author={Yubin Miao and Thomas P Quinn},
  journal={Critical reviews in oncology/hematology},
  year={2008},
  volume={67 3},
  pages={213-28}
}
Melanocortin-1 receptor (MC1-R) and melanin are two attractive melanoma-specific targets for peptide-targeted radionuclide therapy for melanoma. Radiolabeled peptides targeting MC1-R/melanin can selectively and specifically target cytotoxic radiation generated from therapeutic radionuclides to melanoma cells for cell killing, while sparing the normal tissues and organs. This review highlights the recent advances of peptide-targeted radionuclide therapy of melanoma targeting MC1-R and melanin… CONTINUE READING

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