Peptide stability in drug development: a comparison of peptide reactivity in different biological media.

Abstract

Degradation kinetics for several peptides that bind to the major histocompatibility complex on antigen-presenting cells were determined in both human serum (HS; 25%) and synovial fluid (SF; 25%) from patients with rheumatoid arthritis to test whether therapeutic intervention of rheumatoid arthritis by direct intrasynovial injection is feasible (at least in… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.