Peptide sequence determination by matrix-assisted laser desorption ionization employing a tandem double focusing magnetic-Orthogonal acceleration time-of-flight mass spectrometer.

@article{Medzihradszky1996PeptideSD,
  title={Peptide sequence determination by matrix-assisted laser desorption ionization employing a tandem double focusing magnetic-Orthogonal acceleration time-of-flight mass spectrometer.},
  author={Katalin F Medzihradszky and Gregory W. Adams and Alma L. Burlingame and Robert H. Bateman and Martin R. Green},
  journal={Journal of the American Society for Mass Spectrometry},
  year={1996},
  volume={7 1},
  pages={1-10}
}
This report describes the fragmentation processes for peptides induced by collisional activation of the (12)C isobar of matrix-assisted laser desorption ionization (MALDI)-generated pseudomolecular ions employing an EBE orthogonal acceleration time-of-flight mass spectrometer and using xenon as the collision gas at a laboratory collision energy of 800 eV. These MALDI-collision-induced dissociation (CID) spectra are shown to provide sequence information of comparable quality to those obtained by… CONTINUE READING

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