Peptide model systems for amyloid fiber formation: design strategies and validation methods.

Abstract

The rational understanding of the factors involved in the formation of amyloid deposits in tissue is fundamental to the identification of novel therapeutic strategies to prevent or cure pathological conditions such as Alzheimer's and Parkinson's disease or spongiform encephalopathies. Given the complexity of the molecular events driving protein self… (More)

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Cite this paper

@article{EsterasChopo2006PeptideMS, title={Peptide model systems for amyloid fiber formation: design strategies and validation methods.}, author={Alexandra Esteras-Chopo and Mar{\'i}a Teresa Pastor and Manuela L{\'o}pez de la Paz}, journal={Methods in molecular biology}, year={2006}, volume={340}, pages={253-76} }