Peptide-mediated cell transport of water soluble porphyrin conjugates.

Abstract

Five new porphyrin-peptide conjugates bearing a nuclear localizing sequence SV40 or a fusogenic peptide (HIV-1Tat 40-60 or octa-arginine) linked by low molecular weight poly(ethylene glycol) have been synthesized. In vitro studies using human HEp2 cells show that the cellular uptake of the conjugates depends significantly on the nature and sequence of amino… (More)

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@article{SibrianVazquez2006PeptidemediatedCT, title={Peptide-mediated cell transport of water soluble porphyrin conjugates.}, author={Martha Sibrian-Vazquez and Timothy J. Jensen and Robert P. Hammer and M. Graça H. Vicente}, journal={Journal of medicinal chemistry}, year={2006}, volume={49 4}, pages={1364-72} }