Peptide ligand mediated drug delivery to TAMs

Abstract

SUMMARY The microenvironment of solid tumors is characterized by a reactive stroma with an abundance of inflammatory mediators and leukocytes. Tumor associated macrophages (TAMs) were found to play critical roles during the growth and metastasis of malignant tumors. We report in this paper an attempt to deliver drugs into TAMs using a peptide ligand… (More)

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