Peptide ion channel toxins from the bootlace worm, the longest animal on Earth

@inproceedings{Jacobsson2018PeptideIC,
  title={Peptide ion channel toxins from the bootlace worm, the longest animal on Earth},
  author={Erik Jacobsson and H{\aa}kan S. Andersson and Malin Strand and Steve Peigneur and Camilla Eriksson and Henrik Lod{\'e}n and Mohammadreza Shariatgorji and Per E. Andr{\'e}n and Eline K. M. Lebbe and K Johan Rosengren and Jan Tytgat and Ulf G{\"o}ransson},
  booktitle={Scientific Reports},
  year={2018}
}
Polypeptides from animal venoms have found important uses as drugs, pharmacological tools, and within biotechnological and agricultural applications. We here report a novel family of cystine knot peptides from nemertean worms, with potent activity on voltage-gated sodium channels. These toxins, named the α-nemertides, were discovered in the epidermal mucus… CONTINUE READING