Peptide inhibitors against herpes simplex virus infections.

  title={Peptide inhibitors against herpes simplex virus infections.},
  author={Stefania Galdiero and Annarita Falanga and Rossella Tarallo and Luigi Russo and Emilia Galdiero and Marco Cantisani and Giancarlo Morelli and Massimiliano Galdiero},
  journal={Journal of peptide science : an official publication of the European Peptide Society},
  volume={19 3},
Herpes simplex virus (HSV) is a significant human pathogen causing mucocutaneous lesions primarily in the oral or genital mucosa. Although acyclovir (ACV) and related nucleoside analogs provide successful treatment, HSV remains highly prevalent worldwide and is a major cofactor for the spread of human immunodeficiency virus. Encephalitis, meningitis, and blinding keratitis are among the most severe diseases caused by HSV. ACV resistance poses an important problem for immunocompromised patients… CONTINUE READING
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