Peptide and immunochemical mapping of the ectodomain of the porcine LH receptor.

@article{Couture1996PeptideAI,
  title={Peptide and immunochemical mapping of the ectodomain of the porcine LH receptor.},
  author={Laurence Couture and H Naharisoa and Denise Gr{\'e}bert and Jean Jacques Remy and E. Pajot-Augy and V Bozon and Thomas Haertl{\'e} and Roland Salesse},
  journal={Journal of molecular endocrinology},
  year={1996},
  volume={16 1},
  pages={15-25}
}
The LH/hCG receptor is a G protein-coupled receptor with an N-terminal extracellular domain involved in hormone-receptor interaction. The recombinant porcine receptor, stably expressed in Chinese hamster ovary (CHO) cells, has the same characteristics (Kd and cAMP production) as in Leydig cells. Six synthetic peptides derived from the receptor ectodomain and two polyclonal anti-peptide sera were tested in the homologous system porcine LH and porcine LH receptor. Their ability to inhibit hormone… CONTINUE READING