Peptide YY: a neuroendocrine neighbor of note.

  title={Peptide YY: a neuroendocrine neighbor of note.},
  author={Helen M Cox},
  volume={28 2},
Endocrine cells, enteric neurons and enterocytes provide an integrated functional defense against luminal factors, including nutrients, microbes and toxins. Prominent among intrinsic mediators is peptide YY (PYY) which is present in approximately 50% of colorectal endocrine cells and neuropeptide Y (NPY), a neurotransmitter expressed in submucous and myenteric nerves. Both peptides and their long fragments (PYY(3-36) and NPY(3-36)) are potent, long-lasting anti-secretory agents in vitro and in… CONTINUE READING


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Low PYY levels contribute to the development of obesity

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  • Diabetologia
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