Peptic Ulcer Disease and the Risk of Bladder Cancer in a Prospective Study of Male Health Professionals

@article{Michaud2004PepticUD,
  title={Peptic Ulcer Disease and the Risk of Bladder Cancer in a Prospective Study of Male Health Professionals},
  author={Dominique S. Michaud and Pauline A. Mysliwiec and Walid H. Aldoori and Walter C. Willett and Edward L. Giovannucci},
  journal={Cancer Epidemiology Biomarkers \& Prevention},
  year={2004},
  volume={13},
  pages={250 - 254}
}
Helicobacter pylori is a risk factor for gastric and duodenal ulcers, but gastric ulcers generally occur in individuals who have low acid production and diffuse gastritis, whereas duodenal ulcers are more likely to occur with high acid output and antrum-predominant gastritis. Low acid production, gastritis, and ulcer healing each contribute to poor antioxidant absorption, oxidative stress, and elevated nitrite levels in the stomach. N-Nitrosamines are known carcinogens, and nitrate ingestion… Expand
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Gastric and duodenal ulcers, periodontal disease, and risk of bladder cancer in the Health Professionals Follow-up Study
TLDR
A prospective analysis among 45,185 men in the Health Professionals Follow-Up Study did not find sufficient evidence for interaction between gastric/duodenal ulcers and periodontal disease on bladder cancer risk. Expand
Gastric and Duodenal Ulcer and Risk of Bladder Cancer
To the Editors: In the Health Professional Follow-up Study, Michaud et al. ([1][1]) found a 55% increased risk of bladder cancer for subjects with a history of gastric ulcer. Previous epidemiologic… Expand
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There is no evidence that exposure to NDMA through ranitidine increases the risk of cancer, and no significant differences were observed in the analysis of 11 single cancer outcomes. Expand
Oral intake of ranitidine increases urinary excretion of N-nitrosodimethylamine.
TLDR
A need to evaluate the risks attributable to NDMA associated with chronic consumption of ranitidine, and to identify alternative treatments that minimize exposure to N-nitrosamines, is suggested. Expand
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The risk to human health due to nitrate consumption may be minimized by harvesting vegetables at noon, removal of organs rich in nitrate content and cooking of vegetables in water with a low nitrates content. Expand
Factors Responsible for Nitrate Accumulation: A Review
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The risk to human health due to nitrate consumption may be minimized by harvesting vegetables in the noon, removal of organs rich in nitrate content and cooking of vegetables with water having a low nitrate Content. Expand
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Nitrogen is the most abundant element in the atmosphere and a crucial nutrient for the plant growth and development. Nitrate is a major form that plants absorb nitrogen. Vegetables can be considered… Expand
Nitrogen Pollution, Plants and Human Health
Limited supply of reactive nitrogen compounds had been a key constraint to human development before the nineteenth century and mankind would rely heavily and entirely on fossil nitrogen and manure… Expand
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A maior susceptibilidade destas regioes pode ser explicada por sua anatomia microvascular, a qual apresenta capilares estreitos, tortuosos e com menor diâmetro que em outras regoes do estomago. Expand
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