PepX: a structural database of non-redundant protein–peptide complexes

  title={PepX: a structural database of non-redundant protein–peptide complexes},
  author={Peter Vanhee and Joke Reumers and François Stricher and Lies Baeten and Luis Serrano and Joost Schymkowitz and Frederic Rousseau},
  booktitle={Nucleic Acids Research},
Although protein-peptide interactions are estimated to constitute up to 40% of all protein interactions, relatively little information is available for the structural details of these interactions. Peptide-mediated interactions are a prime target for drug design because they are predominantly present in signaling and regulatory networks. A reliable data set of nonredundant protein-peptide complexes is indispensable as a basis for modeling and design, but current data sets for protein-peptide… CONTINUE READING