PepDistiller: A quality control tool to improve the sensitivity and accuracy of peptide identifications in shotgun proteomics.

Abstract

In this study, we presented a quality control tool named PepDistiller to facilitate the validation of MASCOT search results. By including the number of tryptic termini, and integrating a refined false discovery rate (FDR) calculation method, we demonstrated the improved sensitivity of peptide identifications obtained from semitryptic search results. Based… (More)
DOI: 10.1002/pmic.201100167

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@article{Li2012PepDistillerAQ, title={PepDistiller: A quality control tool to improve the sensitivity and accuracy of peptide identifications in shotgun proteomics.}, author={N. M. Li and Songfeng Wu and Chengpu Zhang and Cheng Chang and Jiyang Zhang and Jie Ma and Liwei Li and Xiaohong Qian and Ping Xu and Yunping Zhu and Fuchu He}, journal={Proteomics}, year={2012}, volume={12 11}, pages={1720-5} }