PepD participates in the mycobacterial stress response mediated through MprAB and SigE.

@article{White2010PepDPI,
  title={PepD participates in the mycobacterial stress response mediated through MprAB and SigE.},
  author={Mark J. White and Hongjun He and Renee M. Penoske and Sally S. Twining and Thomas C. Zahrt},
  journal={Journal of bacteriology},
  year={2010},
  volume={192 6},
  pages={1498-510}
}
Currently, one-third of the world's population is believed to be latently infected with Mycobacterium tuberculosis. The mechanisms by which M. tuberculosis establishes latent infection remain largely undefined. mprAB encodes a two-component signal transduction system required by M. tuberculosis for aspects of persistent infection. MprAB regulates a large and diverse group of genetic determinants in response to membrane stress, including the extracytoplasmic function (ECF) sigma factor sigE and… CONTINUE READING