Pentraxin 3 in Cardiovascular Disease

@inproceedings{Ristagno2019Pentraxin3I,
  title={Pentraxin 3 in Cardiovascular Disease},
  author={Giuseppe Ristagno and Francesca Maria Fumagalli and Barbara Bottazzi and Alberto Mantovani and Davide Olivari and Deborah Novelli and Roberto Latini},
  booktitle={Front. Immunol.},
  year={2019}
}
The long pentraxin PTX3 is a member of the pentraxin family produced locally by stromal and myeloid cells in response to proinflammatory signals and microbial moieties. The prototype of the pentraxin family is C reactive protein (CRP), a widely-used biomarker in human pathologies with an inflammatory or infectious origin. Data so far describe PTX3 as a multifunctional protein acting as a functional ancestor of antibodies and playing a regulatory role in inflammation. Cardiovascular disease (CVD… CONTINUE READING

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