Pentraxin-3 expression in acute renal allograft rejection.

@article{Imai2012Pentraxin3EI,
  title={Pentraxin-3 expression in acute renal allograft rejection.},
  author={Naofumi Imai and Shinichi Nishi and Kazuhiro Yoshita and Yumi Ito and Yutaka Osawa and Kaori Takahashi and Yuki Nakagawa and Kazuhide Saito and Kota Takahashi and Ichiei Narita},
  journal={Clinical transplantation},
  year={2012},
  volume={26 Suppl 24},
  pages={
          25-31
        }
}
Pentraxin-3 (PTX3) is an acute phase reactant produced by a variety of cell types at sites of local inflammation. We examined by immunohistochemistry renal biopsies from patients with acute rejection (n = 10), protocol biopsies without rejection (n = 37), and peri-operative donor biopsies of the same transplant patients (n = 94) for intra-renal expression of PTX3, and its correlation with clinical, laboratory, and histopathologic parameters. PTX3 was mainly expressed in the interstitium of… CONTINUE READING

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