• Corpus ID: 30972289

Pentoxifylline-rescue for the oncological patient . Anticancer and protective properties of an alkaloid derivative .

@inproceedings{BoguckaKocka2013PentoxifyllinerescueFT,
  title={Pentoxifylline-rescue for the oncological patient . Anticancer and protective properties of an alkaloid derivative .},
  author={Anna Bogucka-Kocka and Anna Och and Marek Och and Janusz Kocki},
  year={2013}
}
Context: Pentoxifylline is a methylxanthine derivative. Because of influence on blood flow it is a drug used in circulatory diseases. Currently pentoxifylline is under examination as regards its anticancer properties. Objective: The authors gathered and systemized the knowledge about anticancer activity of pentoxifylline and knowledge about the progress of studies and clinical triails in this subject. Methods: More than 80 Englishlanguage abstracts were analyzed and complete texts of selected… 

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The interaction between verapamil and pentoxifylline is, at least partially, P-glycoprotein-mediated, whereas alterations in lisofylline pharmacokinetics are caused by inhibition of drug metabolising enzymes.