Pentoxifylline does not spare acute radiation reactions in rat lung and skin.

  title={Pentoxifylline does not spare acute radiation reactions in rat lung and skin.},
  author={William F. Ward and Yoon Tae Kim and Agostino Molteni and Chung hsin Ts'ao and Joann M. Hinz},
  journal={Radiation research},
  volume={129 1},
Male rats were exposed to single doses (0-30 Gy) of 60Co gamma rays to the right hemithorax. Half of each dose group consumed only control powdered chow after irradiation, and half consumed feed containing 0.10% (w/w) pentoxifylline (50 mg/kg/day). The severity of epilation and desquamation in the field of the radiation port was scored weekly. Two months after irradiation the animals were killed, and pulmonary endothelial function was monitored by the activity of lung angiotensin converting… Expand
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