Pentoxifylline attenuates iminodipropionitrile-induced behavioral abnormalities in rats

@article{Kadasah2009PentoxifyllineAI,
  title={Pentoxifylline attenuates iminodipropionitrile-induced behavioral abnormalities in rats},
  author={Saeed Al Kadasah and Ahmad Al Mutairy and M. Siddiquei and Haseeb Ahmad Khan and Ibrahim Abdulwahid Arif and K. Al Moutaery and M. Tariq},
  journal={Behavioural Pharmacology},
  year={2009},
  volume={20},
  pages={356-360}
}
This investigation was undertaken to study the effect of pentoxifylline (PTX) on iminodipropionitrile (IDPN)-induced behavioral abnormalities [excitation with choreiform and circling movements (ECC) syndrome] in rats. The animals were intraperitoneally injected with IDPN (100 mg/kg) daily for 7 days. PTX was administered daily 30 min before IDPN in the doses of 25, 50, and 100 mg/kg for 9 days. The animals were observed for neurobehavioral abnormalities including dyskinetic head movements… Expand
10 Citations
Histological insights in iminodipropionitrile-induced toxicity in rats.
  • K. E. Ibrahim, H. Khan, F. A. Omer
  • Biology, Medicine
  • Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie
  • 2014
  • 3
Ameliorative effect of gastrodin on 3,3′-iminodipropionitrile-induced memory impairment in rats
  • 8
Gastrodin Attenuates Cognitive Deficits Induced by 3,3′-Iminodipropionitrile
  • 6
Importance of customized (task oriented) software tools for biomedical applications
  • H. Khan
  • Computer Science
  • Bioinformation
  • 2020
  • 1
  • PDF

References

SHOWING 1-10 OF 48 REFERENCES
Attenuation of iminodipropionitrile induced behavioral syndrome by sodium salicylate in rats
  • 27
  • PDF
Sodium benzoate attenuates iminodipropionitrile-induced behavioral syndrome in rats
  • 8
Protective effect of hydrocortisone on iminodipropionitrile-induced neurotoxicity in rats.
  • 14
Metoclopramide attenuates iminodipropionitrile-induced oxidative stress and neurobehavioral toxicity in rats
  • 14
  • Highly Influential
Pentoxifylline ameliorates lithium-pilocarpine induced status epilepticus in young rats
  • 30
Pentoxifylline Prevents Spontaneous Brain Ischemia in Stroke-Prone Rats
  • 40
  • PDF
Partial reversal of the iminodipropionitrile-induced hyperkinetic syndrome in rats by alpha-tocopherol (vitamin E).
  • J. Lohr, J. Cadet, R. Wyatt, W. Freed
  • Psychology, Medicine
  • Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
  • 1988
  • 23
Behavioral syndrome induced by allylnitrile, crotononitrile or 2-pentenenitrile in rats
  • 26
Pentoxifylline attenuates the development of hyperalgesia in a rat model of neuropathic pain
  • 74
...
1
2
3
4
5
...