Pentose Nucleotides in the Cytoplasm of Growing Tissues

  title={Pentose Nucleotides in the Cytoplasm of Growing Tissues},
  author={Torbj{\"o}rn Caspersson and Jack C. Schultz},
INTEREST in the nucleic acid metabolism of mitosis has in general tended to centre on the nucleus. More recently evidence has been obtained showing an interplay between the nucleic acid metabolism of the nucleus and that of the cytoplasm1. Studying the ultra-violet absorption spectra of the cytoplasms of growing tissues, we have found them all to exhibit the maximum around 2600 A., characteristic of the cyclic nitrogenous bases present in the nucleic acids. In contrast, the homologous mature… 
Phosphorus compounds in animal tissues; the nucleic acid content of homologous normal and cancer tissues.
The first direct experimental evidence in support of the hypothesis that DNA is closely associated with, if not in fact identical with, the genes has now appeared.
Phosphorus compounds in animal tissues; the distribution of nucleic acids and other phosphorus-containing compounds in normal and malignant tissues.
It was found that the cancer tissues contained much higher concentrations of nucleic acids than did the normal tissues, and the results have been extended to include a larger number of normal and malignant tissues.
Occurrence of zinc in the nucleoli of mammalian nerve cells and its relation to the growth of the cells
The author's modification of dithizide method for the presence of metal in nucleoli and polarographic analysis of the material for identification with zinc are described, together with further observations with post-natal young as well as with histochemical examination of the dithIZide positive substance.
Quantitative infrared spectrometry of purines and pyrimidines
Alterations in the nucleo-protein of genes are probably directly involved in carcinogenesis and radiotherapy, and a knowledge of the exact nature of these changes implies the possibility of insight into means for their prevention and/or reversal.
Ribonucleic Acids in Animal Tissues
The original view that ribonucleic acids are to be found exclusively in plant tissues, and desoxyribon nucleic acid exclusively in animal tissues is now known to be no longer tenable.
Cytochemical Studies on Chloroplasts I
The localization of depolymerized and highly-polymerized DNA and RNA in the chloroplasts of some higher plants was demonstrated, using cytochemical methods with methyl green and pyronin and Feulgen's
Desoxyribose nucleic acid (DNA) content and size of rat liver nuclei during thioac etamide intoxication and recovery
Summary1.Thioacetamide administered to white rats by the drug-diet method brought about an increase in nuclear DNA content of their liver parenchyma cells in the sense that the frequencies of the