Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells

Abstract

INTRODUCTION This study was undertaken to determine whether the anti-osteoarthritis drug pentosan polysulfate (PPS) influenced mesenchymal precursor cell (MPC) proliferation and differentiation. METHODS Human MPCs were maintained in monolayer, pellet or micromass cultures (MMC) for up to 10 days with PPS at concentrations of 0 to 20 microg/ml. MPC… (More)
DOI: 10.1186/ar2935

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@inproceedings{Ghosh2010PentosanPP, title={Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells}, author={Peter Ghosh and Jiehua Wu and Susan Shimmon and Andrew Zannettino and Stan Gronthos and Silviu Itescu}, booktitle={Arthritis research & therapy}, year={2010} }