Pentobarbital: selective depression of excitatory postsynaptic potentials.

@article{Barker1973PentobarbitalSD,
  title={Pentobarbital: selective depression of excitatory postsynaptic potentials.},
  author={J L Barker and Harold Gainer},
  journal={Science},
  year={1973},
  volume={182 4113},
  pages={720-2}
}
The effects of pentobarbital (Nembutal) on synaptic transmission and postsynaptic potentials were studied by the use of several invertebrate preparations. Pentobarbital selectively and reversibly depressed both excitatory postsynaptic potentials and sodium-dependent postsynaptic responses to putative excitatory transmitters without affecting either inhibitory postsynaptic potentials or chloride- and potassium-dependent postsynaptic responses to putative transmitters. A selective depression of… CONTINUE READING

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