Pentavalent rotavirus vaccine in developing countries: safety and health care resource utilization.

@article{Christie2010PentavalentRV,
  title={Pentavalent rotavirus vaccine in developing countries: safety and health care resource utilization.},
  author={Celia D. C. Christie and Newton D. Duncan and Kirk A Thame and Matthew T. Onorato and Hyacinth D Smith and Lavern G Malcolm and Robbin F. Itzler and Mark J Dinubile and Penny M. Heaton},
  journal={Pediatrics},
  year={2010},
  volume={126 6},
  pages={e1499-506}
}
OBJECTIVE In the international, placebo-controlled, Rotavirus Efficacy and Safety Trial, the pentavalent rotavirus vaccine reduced the rate of rotavirus-attributable hospitalizations and emergency department visits by 95%. This study investigated the effect in Jamaica. METHODS The vaccine effect on rates of hospitalizations and emergency department visits in Jamaica was evaluated in both modified intention-to-treat and per-protocol analyses. Rates of serious adverse events, including… CONTINUE READING
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