Pentatricopeptide repeat proteins in Trypanosoma brucei function in mitochondrial ribosomes.

  title={Pentatricopeptide repeat proteins in Trypanosoma brucei function in mitochondrial ribosomes.},
  author={Mascha Pusnik and Ian Small and Laurie K. Read and Thomas Fabbro and Andr{\'e} Schneider},
  journal={Molecular and cellular biology},
  volume={27 19},
The pentatricopeptide repeat (PPR), a degenerate 35-amino-acid motif, defines a novel eukaryotic protein family. Plants have 400 to 500 distinct PPR proteins, whereas other eukaryotes generally have fewer than 5. The few PPR proteins that have been studied have roles in organellar gene expression, probably via direct interaction with RNA. Here we show that the parasitic protozoan Trypanosoma brucei encodes 28 distinct PPR proteins, an extraordinarily high number for a nonplant organism. A… CONTINUE READING
44 Citations
43 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 44 extracted citations


Publications referenced by this paper.
Showing 1-10 of 43 references

The multifarious roles of PPR proteins in plant mitochondrial gene expression

  • C. Andrés, C. Lurin, I. D. Small
  • 2007
1 Excerpt

Similar Papers

Loading similar papers…