Penn State screen exam for the detection of frontal and temporal dysfunction syndromes: application to ALS.

@article{FlahertyCraig2009PennSS,
  title={Penn State screen exam for the detection of frontal and temporal dysfunction syndromes: application to ALS.},
  author={Claire V Flaherty-Craig and Allyson F Brothers and Brandon Dearman and Paul J. Eslinger and Zachary Simmons},
  journal={Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases},
  year={2009},
  volume={10 2},
  pages={107-12}
}
We improved standard treatment approaches by systematically addressing cognitive and behavioral change in association with frontal and temporal dysfunction in ALS. We evaluated the profile of inchange 198 ALS patients with a 20-minute screen exam. Significant deficiencies in letter fluency and reading comprehension (N=59) were found in 22.7% and 12.8% of limb onset and 36.4% and 20% of bulbar-onset patients. Deficiencies in abstract reasoning and judgment were found in 17%, and 29.5% of limb… CONTINUE READING

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