Penicillin in infants weighing two kilograms or less with early-onset Group B streptococcal disease.

@article{Pyati1983PenicillinII,
  title={Penicillin in infants weighing two kilograms or less with early-onset Group B streptococcal disease.},
  author={Suma Pyati and Rosita S. Pildes and Norm Jacobs and Rajam S Ramamurthy and Tsu Fu Yeh and Ditina Raval and L. Lilien and P L S Amma and W I Metzger},
  journal={The New England journal of medicine},
  year={1983},
  volume={308 23},
  pages={1383-9}
}
We studied the effect of penicillin on early-onset Group B streptococcal disease over a 52-month period in neonates who were at high risk of infection. Shortly after birth, 1187 neonates weighing 2000 g or less had blood samples taken for cultures and were randomized into an early-treatment group (given intramuscular penicillin G within 60 minutes of birth) or a control group. The incidence of early-onset disease was 20 per 1000 live births (24 of 1187); the number of infants in the early… CONTINUE READING
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