Penicillin allergy: A practical guide for clinicians

@article{GonzalezEstrada2015PenicillinAA,
  title={Penicillin allergy: A practical guide for clinicians},
  author={Alexei Gonzalez-Estrada and Cristine Radojicic},
  journal={Cleveland Clinic Journal of Medicine},
  year={2015},
  volume={82},
  pages={295 - 300}
}
Penicillin allergy is the most commonly reported drug allergy in the United States. However, after undergoing a complete evaluation by a board-certified allergist, including skin testing, 90% of patients labeled as “penicillin-allergic” are able to tolerate penicillin. Clinical presentation is key in classifying reactions as either mediated by or not mediated by immunoglobulin E (IgE), and in determining which patients may benefit from penicillin skin testing, graded-dose challenge, or… 

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