Penetration of the blood-brain barrier by peripheral neuropeptides: new approaches to enhancing transport and endogenous expression

@article{Lee2018PenetrationOT,
  title={Penetration of the blood-brain barrier by peripheral neuropeptides: new approaches to enhancing transport and endogenous expression},
  author={Mark Robert Lee and Raval Dhwani Jayant},
  journal={Cell and Tissue Research},
  year={2018},
  volume={375},
  pages={287-293}
}
The blood-brain barrier (BBB) is a structural and functional barrier between the interstitial fluid of the brain and the blood; the barrier maintains the precisely controlled biochemical environment that is necessary for neural function. This constellation of endothelial cells, macrophages, pericytes, and astrocytes forms the neurovascular unit which is the structural and functional unit of the blood-brain barrier. Peptides enter and exit the CNS by transport systems expressed by the capillary… CONTINUE READING

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