Penetration of pefloxacin into human allograft pancreatic juice.

  title={Penetration of pefloxacin into human allograft pancreatic juice.},
  author={A-S. Malmborg and Christina Brattstr{\"o}m and Gunnar Tyd{\'e}n},
  journal={The Journal of antimicrobial chemotherapy},
  volume={25 3},
The penetration of pefloxacin (400 mg) into pancreatic juice, following a single oral dose, was investigated in five patients subjected to pancreatic transplantation as treatment for insulin-dependent diabetes mellitus. The pancreatic juice was temporarily diverted to the exterior by means of a pancreatic duct catheter. Studies on pure human pancreatic juice were thus made possible. Simultaneous blood and pure pancreatic juice samples were collected at regular intervals for up to 24 h after… CONTINUE READING


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