Penetration of ciprofloxacin into gynecological tissues following oral and intravenous administration.

@article{Goormans1986PenetrationOC,
  title={Penetration of ciprofloxacin into gynecological tissues following oral and intravenous administration.},
  author={E Goormans and Axel A H Dalhoff and Bart A Kazzaz and J H Branolte},
  journal={Chemotherapy},
  year={1986},
  volume={32 1},
  pages={7-17}
}
Penetration activities of ciprofloxacin into female genital tract tissues were studied following a single oral administration of 500 mg and an intravenous injection of 100 mg. Serum and tissue concentrations were within the same order of magnitude 1 and 3 h after oral administration; 3 h after intake of ciprofloxacin, however, tissue concentrations exceeded the corresponding serum levels twofold. Similarly, tissue concentrations following intravenous injection exceeded the corresponding serum… CONTINUE READING