Penem derivatives: beta-lactamase stability and affinity for penicillin-binding proteins in Escherichia coli.

Abstract

Penem derivatives, a new group of beta-lactam antibiotics with potent activities against a wide range of bacteria, including Pseudomonas aeruginosa, were tested for their stability against hydrolysis by beta-lactamases purified from clinical isolates of Morganella morganii. Proteus vulgaris, and Escherichia coli and by a penicillinase from Bacillus cereus… (More)

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@article{Ohya1982PenemDB, title={Penem derivatives: beta-lactamase stability and affinity for penicillin-binding proteins in Escherichia coli.}, author={Susumu Ohya and Yukio Utsui and Shunji Sugawara and Miki Yamazaki}, journal={Antimicrobial agents and chemotherapy}, year={1982}, volume={21 3}, pages={492-7} }