Penehyclidine hydrochloride: a potential drug for treating COPD by attenuating Toll-like receptors

@inproceedings{Xiao2012PenehyclidineHA,
  title={Penehyclidine hydrochloride: a potential drug for treating COPD by attenuating Toll-like receptors},
  author={Hong-tao Xiao and Zhi Liao and Rong-sheng Tong},
  booktitle={Drug design, development and therapy},
  year={2012}
}
BACKGROUND The aim of this review was to evaluate and summarize the available scientific information on penehyclidine hydrochloride (PHC) for the treatment of chronic obstructive pulmonary disease (COPD) as a result of its ability to attenuate Toll-like receptors. Penehyclidine hydrochloride is an anticholinergic drug manufactured in China, with both antimuscarinic and antinicotinic activity. PHC is used widely in the clinic as a reversal agent in cases of organic phosphorus poisoning and soman… CONTINUE READING
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