Penasins A-E, long-chain cytotoxic sphingoid bases, from a marine sponge Penares sp.

@article{Ando2010PenasinsAL,
  title={Penasins A-E, long-chain cytotoxic sphingoid bases, from a marine sponge Penares sp.},
  author={Hideki Ando and Reiko Ueoka and Shigeru Okada and Tsuyoshi Fujita and Takashi Iwashita and Takaaki Imai and Tomoya Yokoyama and Yuji Matsumoto and Rob W. M. van Soest and Shigeki Matsunaga},
  journal={Journal of natural products},
  year={2010},
  volume={73 11},
  pages={
          1947-50
        }
}
Five sphingoid bases, penasin A (1), penasin B (2), and a mixture of penasins C-E (3-5), were identified from a marine sponge Penares sp. as cytotoxic constituents. The structure of the common polar head part was assigned by analysis of the NMR data, whereas the structures of the long aliphatic chains including the locations of double bond(s) and a branched methyl group were determined by analysis of tandem FABMS and (13)C NMR data together with the GC-MS analysis of ozonolysis products. The… Expand
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