Corpus ID: 232076405

Penalized Poisson model for network meta-analysis of individual patient time-to-event data

  title={Penalized Poisson model for network meta-analysis of individual patient time-to-event data},
  author={E. Ollier and P. Blanchard and G. Teuff and S. Michiels},
Network meta-analysis (NMA) allows the combination of direct and indirect evidence from a set of randomized clinical trials. Performing NMA using individual patient data (IPD) is considered as a gold standard approach as it provides several advantages over NMA based on aggregate data. For example, it allows to perform advanced modelling of covariates or covariate-treatment interactions. An important issue in IPD NMA is the selection of influential parameters among terms that account for… Expand

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