Pemphigus vulgaris IgG cause loss of desmoglein-mediated adhesion and keratinocyte dissociation independent of epidermal growth factor receptor.

Abstract

Autoantibody-induced cellular signaling mechanisms contribute to the pathogenesis of autoimmune blistering skin disease pemphigus vulgaris (PV). Recently, it was proposed that epidermal growth factor receptor (EGFR) might be involved in PV signaling pathways. In this study, we investigated the role of EGFR by comparing the effects of epidermal growth factor… (More)
DOI: 10.2353/ajpath.2009.080392

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Cite this paper

@article{Heupel2009PemphigusVI, title={Pemphigus vulgaris IgG cause loss of desmoglein-mediated adhesion and keratinocyte dissociation independent of epidermal growth factor receptor.}, author={W M Heupel and Peter Engerer and Enno Schmidt and Jens Waschke}, journal={The American journal of pathology}, year={2009}, volume={174 2}, pages={475-85} }