Pemetrexed in advanced non-small-cell lung cancer

  title={Pemetrexed in advanced non-small-cell lung cancer},
  author={A. Fuld and K. Dragnev and J. Rigas},
  journal={Expert Opinion on Pharmacotherapy},
  pages={1387 - 1402}
  • A. Fuld, K. Dragnev, J. Rigas
  • Published 2010
  • Medicine
  • Expert Opinion on Pharmacotherapy
  • Importance of the field: Current therapeutic options for advanced non-small-cell lung cancer (NSCLC) yield relatively modest improvements in survival leading to an ongoing search for new active treatment agents. In the past decade, pemetrexed has had an increasingly established role in the treatment of advanced NSCLC in both first- and second-line settings. Areas covered in this review: Currently available published data on mechanism of action, pharmacokinetics, safety and efficacy of… CONTINUE READING
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