Pembrolizumab for the treatment of non-small cell lung cancer.

@article{Lim2016PembrolizumabFT,
  title={Pembrolizumab for the treatment of non-small cell lung cancer.},
  author={Sung Hee Lim and Jong-mu Sun and Se-Hoon Lee and Joonghyun Ahn and Keunchil Park and Myung-Ju Ahn},
  journal={Expert opinion on biological therapy},
  year={2016},
  volume={16 3},
  pages={
          397-406
        }
}
INTRODUCTION Immune checkpoint inhibitors targeting programmed death protein 1 (PD-1) receptor and its ligand, PD-L1, have recently led to significant and durable improvements in the clinical outcomes of some types of cancers including lung cancer. AREAS COVERED Pembrolizumab was approved by the US FDA for the treatment of advanced or metastatic NSCLC whose disease has progressed after other treatments and with tumors that express PD-L1. In the phase I KEYNOTE-001 trial, the overall response… CONTINUE READING
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