Pellagra: Dermatitis, dementia, and diarrhea

@article{Hegyi2004PellagraDD,
  title={Pellagra: Dermatitis, dementia, and diarrhea},
  author={Juraj Hegyi and Robert A. Schwartz and Vladim{\'i}r Hegyi},
  journal={International Journal of Dermatology},
  year={2004},
  volume={43}
}
Pellagra defines systemic disease as resulting from a marked cellular deficiency of niacin. It is characterized by 4 “D’s”: diarrhea, dermatitis, dementia, and death. Diagnosis of pellagra is difficult in the absence of the skin lesions, and is often facilitated by the presence of characteristic ones. The dermatitis begins as an erythema. Acute pellagra resembles sunburn in its first stages, but tanning occurs more slowly than typically in sunburn. Exacerbation follows re‐exposure to sunlight… Expand
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References

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TLDR
A case of a 14-year-old boy with classic symptoms of pellagra, who all his symptoms responded to treatment with nicotinic acid. Expand
Pellagra and the carcinoid syndrome.
TLDR
In a 63-year-old black woman, oral and parenteral administration of niacinamide (nicotinamide; the amide form of niakin) led to rapid clearing of the pellagrous dermatitis. Expand
Pellagra in 2 homeless men.
TLDR
The combination of homelessness, alcohol abuse, and failure to eat regularly--particularly, failure to make use of shelter-based meal programs--may identify people at special risk in contemporary settings. Expand
Pellagra and skin
TLDR
This disease, which killed thousands in the United States as recently as 1930, is all but eradicated as a result of great advances in public health in developed countries and improvements in nutrition and enrichment of wheat flour with nicotinic acid. Expand
Pellagra secondary to 5‐fluorouracil
TLDR
A patient who presented with the typical skin changes of pellagra, and an associated acute deterioration in cerebral function, were exacerbated by treatment with 5‐fluorouracil, indicating the importance of considering nicotinic‐acid deficiency in patients with malignant disease. Expand
Pellagra: a still existing disease
TLDR
Pellagra is no longer the medico-social problem it was in the past but in countries with a low nutritional level it continues to a considerable degree in endemic form and in areas of the so-called 'civilized world' where nutritional problems do not really exist, occasional cases are found. Expand
Isoniazid induced pellagra despite pyridoxine supplementation
TLDR
A case of isoniazid‐induced pellagra which occurred despite pyridoxine supplementation is reported, and drug withdrawal and supplementation with niacin led to a rapid and sustained clinical improvement. Expand
A Plaque of Corn: The Social History of Pellagra
Dermatologists are familiar with the scientific writings of Daphne A. Roe; therefore, it is with a bit of surprise that this book reveals another of her interests. A Plaque of Corn is fascinating andExpand
Pellagra in a patient with an eating disorder
TLDR
Urinary 5‐hydroxy‐indole‐acetic acid was found to be low and it is suggested that this may be a useful screening test for an eating disorder. Expand
[Prevalence of HIV infection in patients with pellagra and pellagra-like erythemas].
TLDR
The findings of this study suggest that the incidence of HIV infection in patients withpellagra and pellagra-like erythema is low, i.e., not higher than in the general population. Expand
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