Pegnology: a review of PEG-ylated systems.

  title={Pegnology: a review of PEG-ylated systems.},
  author={Dipankar Bhadra and Sulekha Bhadra and Parridhi Jain and Narendra Kumar Jain},
  journal={Die Pharmazie},
  volume={57 1},
Polyethylene glycol conjugation or linking with the system is called PEGylation. Many novel drug systems are used for the delivery of drugs and bioactive substances to particular sites in a controlled or sustained manner, but various side effects or shortcomings restrict their use for the intended purpose. The shortcomings such as RES uptake, drug leakage, immunogenicity, stability, hemolytic toxicity etc. can generally be overcome by PEGylation of novel drug delivery systems such as liposomes… CONTINUE READING


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