Pedimune in recurrent respiratory infection and diarrhoea—The Indian experience—The PRIDE study

@article{Patel2006PedimuneIR,
  title={Pedimune in recurrent respiratory infection and diarrhoea—The Indian experience—The PRIDE study},
  author={Kamlesh Patel and Rajiv Rana},
  journal={The Indian Journal of Pediatrics},
  year={2006},
  volume={73},
  pages={585-591}
}
ObjectiveTo evaluate the efficacy and tolerability of bovine colostrum in preventing recurrent episodes of upper respiratory tract infections and diarrhoea in childrenMethods605 children (1–8 yrs) having recurrent episodes of upper respiratory tract infections or diarrhea received Bovine Colostrum (Pedimune®) for 12 weeks. Total no of episodes of recurrent infections, hospitalization rate, overall well being and adverse events were assessed at every 4 weeks.ResultsEpisodes of URTI and diarrhoea… Expand
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References

SHOWING 1-10 OF 68 REFERENCES
Hyperimmune cow colostrum reduces diarrhoea due to rotavirus: a double‐blind, controlled clinical trial
TLDR
Colostrum from cows immunized with rotavirus antigen is clinically effective in reducing the duration and severity of childhood diarrhoea due to rotav virus. Expand
Practical approach to recurrent respiratory infections
TLDR
The author discusses quoting some examples for various categories avoiding non pulmonary causes for recurrent respiratory infections in children. Expand
Concentrated bovine colostrum protein supplementation reduces the incidence of self-reported symptoms of upper respiratory tract infection in adult males
TLDR
Preliminary evidence that CBC may enhance resistance to the development of symptoms of URTI is provided, suggesting that concentrated bovine colostrum protein may prevent upper respiratory tract infection in adult males. Expand
Successful treatment of rotavirus diarrhea in children with immunoglobulin from immunized bovine colostrum.
TLDR
Treatment with antirotavirus immunoglobulin of bovine colostral origin is effective in the management of children with acute rotavirus diarrhea. Expand
Treatment with bovine hyperimmune colostrum of cryptosporidial diarrhea in AIDS patients.
TLDR
It is concluded that hyperimmune colostrum with high titers of specific anti-Cryptosporidium antibody could be effective in treating patients with cryptosporidiosis, but more studies of cow colostral immunoglobulin need to be performed so that the efficacy of this treatment can be assessed more thoroughly. Expand
Immunological investigations in children with recurrent respiratory infections.
TLDR
In this review, a protocol is described which identifies children with severe antibody deficiency by simple screening tests before recurrent infections have caused irrepairable damage to the lungs. Expand
PASSIVE IMMUNISATION OF CHILDREN WITH BOVINE COLOSTRUM CONTAINING ANTIBODIES TO HUMAN ROTAVIRUS
The efficacy of a 10-day course of bovine colostrum with high antibody titre against the four known human rotavirus serotypes in protecting children against rotavirus infection was examined inExpand
Secretory IgA- and IgG-coated bacteria in the nasopharynx of children. An immunofluorescence study.
TLDR
Bacterial samples were obtained from the posterior wall of the nasopharynx of 18 healthy children and subjected for immunofluorescence studies using fluorescein-labelled goat anti-human IgG and goatAnti-human SIgA antibodies, and non-pathogens dominated the bacterial flora. Expand
Bactericidal effect of bovine normal and immune serum, colostrum and milk against Helicobacter pylori.
TLDR
Systemic, serial immunization of non-lactating, pregnant cows with H. pylori resulted in high specific antibody titres in serum and colostrum, but no titres were found in post-colostral milk, even after booster-immunization during lactation. Expand
Early nutrition and the development of immune function in the neonate
TLDR
The present review will concentrate on the development of the gut-associated lymphoid tissue and the role of early nutrition in promoting immune function, the largest immune organ in the body, and the location for the majority of lymphocytes and other immune effector cells. Expand
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