Pedigree discriminant analysis of two French Canadian Tay-Sachs families.


Two French Canadian families among whom the Tay-Sachs allele is segregating are analyzed to investigate whether there is residual phenotypic familial covariation over and above that from major gene segregation. The traits analyzed are functions of hexosaminidase A (HEXA) and hexosaminidase B (HEXB) levels, and a combination of segregation and discriminant… (More)


  • Presentations referencing similar topics