Pediatric posterior fossa ganglioglioma: unique MRI features and correlation with BRAF V600E mutation status

@article{Lindsay2014PediatricPF,
  title={Pediatric posterior fossa ganglioglioma: unique MRI features and correlation with BRAF V600E mutation status},
  author={Aaron J. Lindsay and Sarah Z. Rush and Laura Z. Fenton},
  journal={Journal of Neuro-Oncology},
  year={2014},
  volume={118},
  pages={395-404}
}
Ganglioglioma (GG) is a rare pediatric brain tumor (1–4 %) with neoplastic glial and neuronal cells. Posterior fossa GGs (PF GGs) occur less frequently than supratentorial GGs (ST GGs). The BRAF V600E mutation has been reported in GGs and carries therapeutic implications. We compare the presenting symptoms, magnetic resonance imaging, BRAF V600E mutation status, treatment, and prognosis in children with ST and PF GGs. The neuro-oncology database at a tertiary care Children’s Hospital was… CONTINUE READING
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