Pediatric pharmacokinetic data: implications for environmental risk assessment for children.

  title={Pediatric pharmacokinetic data: implications for environmental risk assessment for children.},
  author={Gary L. Ginsberg and Dale B. Hattis and Richard Miller and Babasaheb R. Sonawane},
  volume={113 4 Suppl},
Pharmacology and toxicology share a common interest in pharmacokinetic data, especially as it is available in pediatric populations. These data have been critical to the clinical pharmacologist for many years in designing age-specific dosing regimens. Now they are being used increasingly by toxicologists to understand the ontogeny of physiologic parameters that may affect the metabolism and clearance of environmental toxicants. This article reviews a wide range of physiologic and metabolic… CONTINUE READING

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