Pediatric oncology group utilization of immunologic markers in the designation of acute lymphocytic leukemia subgroups: influence on treatment response.

@article{Pullen1984PediatricOG,
  title={Pediatric oncology group utilization of immunologic markers in the designation of acute lymphocytic leukemia subgroups: influence on treatment response.},
  author={Daniel Pullen and James M. Boyett and William M. Crist and John M Falletta and Marc Roper and Barry L. Dowell and Jan van Eys and Jacquelyn Ford Jackson and Greer B. Humphrey and Richard S. Metzgar},
  journal={Annals of the New York Academy of Sciences},
  year={1984},
  volume={428},
  pages={26-48}
}
The clinical application of blast cell immunophenotype testing is important in childhood ALL for the following reasons. (1) Knowledge of the immunologic group is important in predicting prognosis. Prognostic grouping may prove to be accomplished best by using a combination of traditional risk factors and immunologic phenotyping. However, definition of traditional risk factors may vary within the immunologic groups of ALL. (2) In assessing the relative effectiveness of different treatment… CONTINUE READING

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